Neuronale Zeroidlipofuszinose 8 (NCL-8) - Saluki ISAG Affected dogs often have to

Affected dogs often have to be on a strict low-fat diet to retain normal neurological function

Symptoms of the kidney cancer include blood in urine

Klinische Anzeichen werden sichtbar

Mutation: LAMP3 gene

Das Gehirn zeigt eine schwere Degeneration und Nekrose von Neuronen

Neuronale Zeroidlipofuszinose 8 (NCL-8) - Saluki ISAG Affected dogs often have toNeuronal ceroid lipofuscinosis (NCLs) are a group of hereditary diseases, characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina, and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate