Leukodystrophie (LEP) Diversität Betroffene Hunde zeigen Anzeichen von

Betroffene Hunde zeigen Anzeichen von Photophobie bei vollem Sonnenlicht

Clinical signs in Leonberger vary greatly and have different age of onset from <1 year to 10 years of age

Digital documentation for breeding and health management

Processing time after sample receipt in the laboratory: usually 2 - 3 weeks

Mutation: ANO6 gene

Leukodystrophie (LEP) Diversität Betroffene Hunde zeigen Anzeichen vonLeukodystrophy (LEP) is an autosomal recessive disorder affecting the white matter of the central nervous system. The symptoms show postnatal and include apathy, dysphoric vocalization, hypermetric ataxia, intension tremor, head tilts, circling, proprioceptive deficits, seizures, ventral strabismus and weakness. The affected puppies often have to be euthanised due to severe symptoms and the risk of a sudden death. Inheritance: autosomal recessive