Akrales Mutilationssyndrom (AMS) Startseite Betroffene Männchen und Trägerweibchen entwickeln

Betroffene Männchen und Trägerweibchen entwickeln spontan Proteinurie

footpad lesions

skin cancer

Footpad hyperkeratosis is an autosomal recessive disorder

symptoms disappear when puppies are at rest or asleep

Akrales Mutilationssyndrom (AMS) Startseite Betroffene Männchen und Trägerweibchen entwickelnAcral mutilation syndrome (AMS) is a neurological disease characterized by insensitivity to pain in peripheral parts of the body (limbs, fingers, toes), combined with self mutilation. Clinical signs appear in puppies approximately four months old when they begin to lick and bite their paws. Affected dogs present an acral insensitivity to pain with, in the majority of cases, severe self mutilations of the feet including claw loss, painless fractures,