Shedding, Haaren Für Tierbesitzer complete color blindness and decreased

complete color blindness and decreased central visual acuity

It is characterized by defect of MCAD enzyme that is crucial for metabolism of medium-chain fatty acids (MCFAs) that serve as energy source for the body

loss of coordination

It allows expression of A-Locus

All affected dogs will develop POAG or PLL or both of them

Shedding, Haaren Für Tierbesitzer complete color blindness and decreasedReduced hair shedding (MC5R) is a complex genetic trait that can affect all breeds and has epistatic interactions with FGF5 (coat length) and RSPO2 (furnishing), which also affect hair morphology in dogs. These loci have undergone selective sweeps due to a strong artificial selection for fur phenotype. The MC5R protein sequence is evolutionarily conserved across mammals, and a certain mutation causes a conformational change in the tertiary structure